Cardiac-specific Suv39h1 knockout ameliorates high-fat diet induced diabetic cardiomyopathy via regulating Hmox1 transcription
These results suggested that the protective effects in DCM rendered by Suv39h1 ablation may work through activating Hmox1 transcription and protein function, providing new insights into pathogenesis of DCM and novel epigenetic target for clinical DCM therapies.
Authors
- Xiangyu Kong (ORCID: https://orcid.org/0000-0001-7515-2613)
- Maohui Chen (ORCID: https://orcid.org/0000-0001-6931-8875)
- Ke Sun (ORCID: https://orcid.org/0000-0001-6730-0014)
- Li Liu (ORCID: https://orcid.org/0000-0002-8054-562X)
- Zhiwei Xu (ORCID: https://orcid.org/0000-0002-9278-2083)
- Weiyuan Hou
Institutions
- Nanjing Normal University (CN)
- Xuzhou Medical College (CN)
- Second People’s Hospital of Huai’an (CN)
- Nanjing Medical University (CN)
Publication Details
- Journal
- Life Sciences
- Published
- 2024-11-22
- DOI
- https://doi.org/10.1016/j.lfs.2024.123258
- Citations
- 2
- Primary Topic
- Congenital heart defects research
- Type
- article
- Field-Weighted Citation Impact
- 0.47
Funders
- National Natural Science Foundation of China