Effect of microtextured titanium sheets using laser enhances proliferation and collagen synthesis of mouse fibroblasts via the TGF-β/Smad pathway
Our findings demonstrate that laser-fabricated hexagonal microtextured titanium sheets enhance hydrophilicity and promote fibroblast growth, activating the TGF-β/Smad pathway to facilitate collagen synthesis. These results have important implications for tissue repair and regeneration.
Authors
- Ruo Feng
- Weihua Fu (ORCID: https://orcid.org/0000-0003-2576-865X)
- Qiang Song (ORCID: https://orcid.org/0000-0002-5923-0842)
- Zhuo Liu (ORCID: https://orcid.org/0000-0002-4425-6185)
- Bang Liu (ORCID: https://orcid.org/0000-0002-3539-6020)
- Peiyao Wang (ORCID: https://orcid.org/0000-0002-8549-4075)
- Haoyu He (ORCID: https://orcid.org/0000-0002-5043-622X)
- Yahui Hu (ORCID: https://orcid.org/0000-0003-0291-8918)
Institutions
- Tianjin University of Technology (CN)
- Tianjin Medical University General Hospital (CN)
- Baotou Central Hospital (CN)
Publication Details
- Journal
- BioMedical Engineering OnLine
- Published
- 2024-11-22
- DOI
- https://doi.org/10.1186/s12938-024-01313-0
- Citations
- 3
- Primary Topic
- Bone Tissue Engineering Materials
- Type
- article
- Field-Weighted Citation Impact
- 0.55
Funders
- Natural Science Foundation of Tianjin City
- Tianjin Medical University