Immunosuppressants in dermatology on vaccine immunogenicity: a prospective cohort study of pemphigus patients in the pandemic

Except for a subset of patients with unrecovered B-cell deficiency, rituximab infusion with proper scheduling of vaccination preserved better anti-viral T-cell responses and did not lead to hindered antibody responses in pemphigus patients. All pemphigus patients benefited from receiving the third booster regardless of B-cell status.

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Publication Details

Journal
Frontiers in Immunology
Published
2024-11-22
DOI
https://doi.org/10.3389/fimmu.2024.1506962
Primary Topic
Autoimmune Bullous Skin Diseases
Type
article
Field-Weighted Citation Impact
0.00

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article

Immunosuppressants in dermatology on vaccine immunogenicity: a prospective cohort study of pemphigus patients in the pandemic

Chuang‐Wei Wang, Rosaline Chung‐Yee Hui, Chun‐Wei Lu, Ya‐Ching Chang et al.
Frontiers in Immunology
Autoimmune Bullous Skin Diseases
article

Immunosuppressants in dermatology on vaccine immunogenicity: a prospective cohort study of pemphigus patients in the pandemic

Chuang‐Wei Wang, Rosaline Chung‐Yee Hui, Chun‐Wei Lu, Ya‐Ching Chang, Chun‐Bing Chen, Kun‐Lin Lu, Wen‐Hung Chung, Hua-En Lee
article en

Abstract

Except for a subset of patients with unrecovered B-cell deficiency, rituximab infusion with proper scheduling of vaccination preserved better anti-viral T-cell responses and did not lead to hindered antibody responses in pemphigus patients. All pemphigus patients benefited from receiving the third booster regardless of B-cell status.

Frontiers in ImmunologyVol. 15
Chang Gung University (TW), Shanghai Jiao Tong University (CN), National Tsing Hua University (TW), Ruijin Hospital (CN), Chang Gung Memorial Hospital (TW), Keelung Chang Gung Memorial Hospital (TW), Xiamen Chang Gung Hospital (CN), Beijing Tsinghua Chang Gung Hospital (CN), Tsinghua University (CN)
Chang Gung Medical Foundation, Ministry of Science and Technology, Taiwan, Chang Gung Memorial Hospital, Linkou
Good health and well-being
Openalex Percentile: Top 66%
Autoimmune Bullous Skin Diseases
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Immunosuppressants in dermatology on vaccine immunogenicity: a prospective cohort study of pemphigus patients in the pandemic — Chuang‐Wei Wang, Rosaline Chung‐Yee Hui, et al. · Frontiers in Immunology (2024) | TGRS Research Map | TGRS