Global and regional genetic association analysis of ulcerative colitis and type 2 diabetes mellitus and causal validation analysis of two-sample two-way Mendelian randomization
There is a causal relationship between T2DM and UC, where T2DM reduces the risk of UC, while no significant causal relationship was observed from UC to T2DM.
Authors
- Yanping Hu (ORCID: https://orcid.org/0000-0002-5770-2527)
- Xintian Li (ORCID: https://orcid.org/0000-0001-6523-7605)
- Zhenyu Zhao
- Xiaoyan Wang (ORCID: https://orcid.org/0000-0001-7406-5008)
- Zhe Chen (ORCID: https://orcid.org/0000-0001-6977-570X)
- Jun Huang
- Minghan Zhou
- Jun Zeng
Institutions
- Central South University (CN)
- Hunan University of Traditional Chinese Medicine (CN)
- Second Affiliated Hospital of Hunan University of Traditional Chinese Medicine (CN)
- Second Xiangya Hospital of Central South University (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2024-11-22
- DOI
- https://doi.org/10.3389/fimmu.2024.1375915
- Citations
- 4
- Primary Topic
- Inflammatory Bowel Disease
- Type
- article
- Field-Weighted Citation Impact
- 2.20
Funders
- National Natural Science Foundation of China
- Hunan University
- Hunan University of Chinese Medicine