G. vaginalis increases HSV-2 infection by decreasing vaginal barrier integrity and increasing inflammation in vivo
These results suggest <i>G. vaginalis</i> inoculation may be increasing HSV-2 infection by disrupting the epithelial barrier, decreasing protective immune responses and increasing tissue inflammation in the vaginal tract.
Authors
- M. Firoz Mian (ORCID: https://orcid.org/0000-0001-6846-9794)
- Aisha Nazli (ORCID: https://orcid.org/0000-0001-7410-9963)
- Charu Kaushic
- Nuzhat Rahman
- Christina L. Hayes
Institutions
- McMaster University (CA)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2024-11-22
- DOI
- https://doi.org/10.3389/fimmu.2024.1487726
- Citations
- 5
- Primary Topic
- Reproductive tract infections research
- Type
- article
- Field-Weighted Citation Impact
- 1.72
Funders
- Canadian Institutes of Health Research