Effect of hypoxia-induced mIL15 expression on expansion and memory progenitor stem-like TILs in vitro
This study demonstrates the superior persistence of TIL-mIL15-IL2 cells, which may serve as a novel treatment strategy for lung cancer patients.
Authors
- Min Lv
- Xiaohao Lan
- Bin Wang (ORCID: https://orcid.org/0000-0003-1971-1972)
- Yongjie Wang (ORCID: https://orcid.org/0000-0002-0306-3088)
- Yi Zhao (ORCID: https://orcid.org/0000-0003-1755-5582)
- Zhen Sun (ORCID: https://orcid.org/0009-0004-9382-0389)
- Bin Guo (ORCID: https://orcid.org/0000-0002-6515-1913)
- Guosheng Gao
- Zhongjie Yu
- Aotian Xu
- Zhaojun Wu
- Lin Shao
- Hao Wu (ORCID: https://orcid.org/0009-0000-1030-9819)
Institutions
- Qingdao University (CN)
- Affiliated Hospital of Qingdao University (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2024-11-22
- DOI
- https://doi.org/10.3389/fimmu.2024.1450245
- Citations
- 1
- Primary Topic
- CAR-T cell therapy research
- Type
- article
- Field-Weighted Citation Impact
- 0.28
Funders
- Texas Space Grant Consortium
- National Key Research and Development Program of China