Roles of the lncRNAs MEG3, PVT1 and H19 tagSNPs in gastric cancer susceptibility
We revealed significant associations of the H19 rs2107425 and PVT1 rs13255292 genetic variants with GC. Interestingly, the novel SNP‒SNP interaction of H19 and PVT1 tagSNPs had a greater effect than single SNP impacts did on GC risk, providing us with invaluable data to identify potential biological mechanisms involved in the development of GC.
Authors
- Behdad Mostafaiy
- Abbas Yazdanbod (ORCID: https://orcid.org/0000-0002-1381-6717)
- Saeid Latifi‐Navid (ORCID: https://orcid.org/0000-0002-6838-9425)
- Vahid Kholghi‐Oskooei
- Farhad Pourfarzi (ORCID: https://orcid.org/0000-0001-6442-6340)
- Esmat Abdi (ORCID: https://orcid.org/0000-0002-9486-4998)
Institutions
- Sirjan University of Technology (IR)
- Ardabil University of Medical Sciences (IR)
- University of Mohaghegh Ardabili (IR)
Publication Details
- Journal
- BMC Cancer
- Published
- 2024-11-22
- DOI
- https://doi.org/10.1186/s12885-024-13209-2
- Citations
- 3
- Primary Topic
- Cancer-related molecular mechanisms research
- Type
- article
- Field-Weighted Citation Impact
- 0.86
Funders
- National Institute for Medical Research Development