Quantification of intratumoral heterogeneity using habitat-based MRI radiomics to identify HER2-positive, -low and -zero breast cancers: a multicenter study
Our study developed ITH signatures that quantified ITH using habitat-based MRI radiomics, achieving outstanding performance in differentiating HER2-postive and -negative tumors, and further differentiating HER2-low and -zero breast cancers.
Authors
- Xiaoxuan Jia
- Peng Yuan (ORCID: https://orcid.org/0000-0003-4627-8203)
- Nan Hong (ORCID: https://orcid.org/0000-0003-1453-273X)
- Fan Chai
- Jiaqi Zhao (ORCID: https://orcid.org/0000-0002-3564-5090)
- Yulu Liu (ORCID: https://orcid.org/0000-0001-6024-1701)
- Haoquan Chen
- Yi Wang (ORCID: https://orcid.org/0009-0004-0665-5945)
- Shu Wang (ORCID: https://orcid.org/0009-0002-4312-0865)
Institutions
- Peking University (CN)
- Peking University People's Hospital (CN)
- Jiangmen Central Hospital (CN)
Publication Details
- Journal
- Breast Cancer Research
- Published
- 2024-11-22
- DOI
- https://doi.org/10.1186/s13058-024-01921-7
- Citations
- 25
- Primary Topic
- Radiomics and Machine Learning in Medical Imaging
- Type
- article
- Field-Weighted Citation Impact
- 10.11