Antibacterial Therapy Options for Infections Caused by Carbapenem-Resistant Acinetobacter baumannii
The review presents current treatment regimens for infections associated with carbapenem-resistant Acinetobacter baumannii , which are leading nosocomial pathogens exhibiting multidrug resistance to available antibacterial drugs. To date, widely used beta-lactam antibiotics, including carbapenems, have lost their effectiveness in combating acinetobacter infections, while new antibiotics remain poorly available to patients. Therefore, the only measure to combat the antibiotic resistance of carbapenem-resistant A. baumannii is to evaluate the efficiency of combination therapy in vitro and in vivo, which is of particular interest to Russian and foreign researchers.
Authors
- Nikita S. Gladyshev (ORCID: https://orcid.org/0000-0003-2732-5676)
- N. E. Goncharov (ORCID: https://orcid.org/0000-0002-6097-5091)
- Vladimir Gostev (ORCID: https://orcid.org/0000-0002-3480-8089)
- O. S. Kalinogorskaya (ORCID: https://orcid.org/0000-0003-1419-9068)
- Alina R Goncharova (ORCID: https://orcid.org/0009-0009-6559-7892)
Institutions
- Saint Petersburg Pasteur Institute (RU)
- Research Institute of Human Morphology (RU)
- North-Western State Medical University named after I.I. Mechnikov (RU)
- Federal Medical-Biological Agency (RU)
Publication Details
- Journal
- Antibiot Khimioter = Antibiotics and Chemotherapy
- Published
- 2024-11-21
- DOI
- https://doi.org/10.37489/0235-2990-2024-69-7-8-53-66
- Citations
- 1
- Primary Topic
- Antibiotic Resistance in Bacteria
- Type
- article
- Field-Weighted Citation Impact
- 0.17
Funders
- National Research Centre
- Ministry of Health of the Russian Federation
- NIH Clinical Center