New Targets for Treating Cancer: Copper Death and Copper Accumulation in Cancer Cells
The accumulation of copper ions plays an important role in the apoptosis of cancer cells. Definition of copper death: Copper death (Cuproptosis) is a new form of programmed cell death caused by excessive copper. Copper ions can participate in multiple cellular signaling pathways and promote the growth and division of cancer cells. Copper ions are involved in angiogenesis, providing nutrients and oxygen for cancer cells and supporting the growth and spread of tumors. Together, they promote the progression of cellular inflammation. Copper ions are related to tumor metastasis and play a certain role in the migration and invasion of cancer cells.
Authors
- Xue Gao (ORCID: https://orcid.org/0000-0002-5927-5805)
- Qingqing Wei (ORCID: https://orcid.org/0000-0002-1692-2451)
- He Tian (ORCID: https://orcid.org/0000-0002-5388-0297)
- Shaofeng Zhao (ORCID: https://orcid.org/0009-0008-0711-6029)
- Hongxia Li
Publication Details
- Journal
- International Journal of Biology and Life Sciences
- Published
- 2024-11-22
- DOI
- https://doi.org/10.54097/9v67nn75
- Primary Topic
- Trace Elements in Health
- Type
- article
- Field-Weighted Citation Impact
- 0.00