Neurologic Manifestations of Long <scp>COVID</scp> Disproportionately Affect Young and Middle‐Age Adults
Younger and middle-age individuals are disproportionally affected by Neuro-PASC regardless of acute COVID-19 severity. Although older people more frequently have abnormal neurologic findings and comorbidities, younger and middle-age patients suffer from a higher burden of Neuro-PASC symptoms and cognitive dysfunction contributing to decreased QoL. Neuro-PASC principally affects adults in their prime, contributing to profound public health and socioeconomic impacts warranting dedicated resources for prevention, diagnosis and interventions. ANN NEUROL 2025;97:369-383.
Authors
- Ayush Batra (ORCID: https://orcid.org/0000-0002-4783-5801)
- Shreya Mukherjee
- Igor J. Koralnik (ORCID: https://orcid.org/0000-0001-6836-1468)
- Tracey Singer
- Eric M. Liotta (ORCID: https://orcid.org/0000-0003-3182-585X)
- Janet L. Miller (ORCID: https://orcid.org/0000-0002-2292-5501)
- Aditi Venkatesh (ORCID: https://orcid.org/0000-0001-6933-6504)
- Millenia Jimenez
- Gina S. Perez Giraldo
- Natasha A. Choudhury (ORCID: https://orcid.org/0000-0002-4321-7344)
- Aasheeta Parikh Bawa
- Melissa Lopez
- Barbara A. Hanson
Institutions
- Northwestern University (US)
- Northwestern Medicine (US)
Publication Details
- Journal
- Annals of Neurology
- Published
- 2024-11-22
- DOI
- https://doi.org/10.1002/ana.27128
- Citations
- 30
- Primary Topic
- Long-Term Effects of COVID-19
- Type
- article
- Field-Weighted Citation Impact
- 11.07
Funders
- National Institutes of Health
- National Institute on Aging