Emergence of Escherichia coli ST131 carrying carbapenemase genes, European Union/European Economic Area, August 2012 to May 2024
Analysis of 594 isolates of <i>Escherichia coli</i> sequence type (ST)131 and its single locus variants carrying carbapenemase genes from 17 European Union/European Economic Area countries revealed acquisition of 18 carbapenemase variants, mainly in ST131 clades A and C. Most frequent were <i>bla</i> <sub>OXA-244</sub> (n = 230) and <i>bla</i> <sub>OXA-48</sub> (n = 224), detected in 14 and 12 countries, respectively. Isolates carrying <i>bla</i> <sub>OXA-244</sub> have increased rapidly since 2021. The increasing detection of carbapenemase genes in the <i>E. coli</i> high-risk lineage ST131 is a public health concern.
Authors
- Marie Meo
- Barbro Mäkitalo
- Algirdas Griškevičius
- Petra Apfalter
- Daan W. Notermans (ORCID: https://orcid.org/0000-0002-9494-0989)
- Mateja Pirš (ORCID: https://orcid.org/0000-0003-2858-9876)
- Anke Kohlenberg
- Vilhelm Müller (ORCID: https://orcid.org/0000-0002-4554-2124)
- Reinis Vangravs (ORCID: https://orcid.org/0000-0001-9067-8912)
- Urška Kramar
- Ørjan Samuelsen (ORCID: https://orcid.org/0000-0002-5525-2614)
- Kateřina Chudějová (ORCID: https://orcid.org/0000-0002-5370-3231)
- Laurent Dortet (ORCID: https://orcid.org/0000-0001-6596-7384)
- Rémy A. Bonnin (ORCID: https://orcid.org/0000-0002-2307-3232)
- Jessica Eisfeld
- Ákos Tóth (ORCID: https://orcid.org/0000-0003-0048-567X)
- Pierre Bogaerts (ORCID: https://orcid.org/0000-0002-4016-3707)
- Manuela Caniça (ORCID: https://orcid.org/0000-0002-2077-6231)
- Olov Svartström (ORCID: https://orcid.org/0000-0003-3100-5325)
- Martin Cormican (ORCID: https://orcid.org/0000-0002-8023-1882)
- Anette M. Hammerum (ORCID: https://orcid.org/0000-0001-9471-1601)
- Lucia Mališová (ORCID: https://orcid.org/0000-0002-3737-6656)
- Ciaran Clarke (ORCID: https://orcid.org/0000-0002-3191-8901)
- Dominique L. Monnet (ORCID: https://orcid.org/0009-0002-7810-1859)
- Marius Linkevičius (ORCID: https://orcid.org/0000-0001-5760-2721)
- Erik Alm (ORCID: https://orcid.org/0000-0002-2903-607X)
- Vera Manageiro (ORCID: https://orcid.org/0000-0001-7729-4199)
- Antoni P. A. Hendrickx (ORCID: https://orcid.org/0000-0003-4431-9323)
- Mirco Sandfort (ORCID: https://orcid.org/0000-0001-7078-6537)
- Baiba Niedre-Otomere (ORCID: https://orcid.org/0000-0001-8822-8680)
- Daniel Palm (ORCID: https://orcid.org/0000-0002-2354-5498)
- Kinga Tóth (ORCID: https://orcid.org/0000-0002-6352-777X)
- Kati Räisänen (ORCID: https://orcid.org/0000-0001-8681-5689)
- Louise Roer (ORCID: https://orcid.org/0000-0001-6892-913X)
- Rainer Hartl (ORCID: https://orcid.org/0000-0002-9007-6089)
- Te-Din Huang
- Kirstin Khonyongwa
Institutions
- Statens Serum Institut (DK)
- University Hospital of North Norway (NO)
- Public Health Agency of Sweden (SE)
- University of Ljubljana (SI)
- Inserm (FR)
- Ollscoil na Gaillimhe – University of Galway (IE)
- Charles University (CZ)
- Robert Koch Institute (DE)
- Commissariat à l'Énergie Atomique et aux Énergies Alternatives (FR)
- Université Paris-Saclay (FR)
- University Hospital Galway (IE)
- Finnish Institute for Health and Welfare (FI)
- Riga East University Hospital (LV)
- National Institute for Public Health and the Environment (NL)
- CEA Paris-Saclay (FR)
- Krankenhaus der Elisabethinen (AT)
- National Laboratory of Health, Environment and Food (SI)
- CNR de la Résistance aux Antibiotiques (FR)
- National Institute of Public Health (CZ)
- National Institute of Health Dr. Ricardo Jorge (PT)
- Laboratoire National de Santé (LU)
- University Hospital Kralovske Vinohrady (CZ)
- European Centre for Disease Prevention and Control (SE)
- Ruhr University Bochum (DE)
Publication Details
- Journal
- Eurosurveillance
- Published
- 2024-11-21
- DOI
- https://doi.org/10.2807/1560-7917.es.2024.29.47.2400727
- Citations
- 19
- Primary Topic
- Antibiotic Resistance in Bacteria
- Type
- article
- Field-Weighted Citation Impact
- 3.24