Predictive Model for Outcomes in Inflammatory Bowel Disease Patients Receiving Maintenance Infliximab Therapy
Using unbiased variable selection, a 2-predictor model using infliximab concentrations and histology identified IBD patients on maintenance infliximab therapy at high risk of future unfavorable outcomes. For practical applicability, infliximab concentrations alone performed similarly well.
Authors
- Ellen Scherl (ORCID: https://orcid.org/0000-0002-8599-4045)
- Rochelle Wong (ORCID: https://orcid.org/0000-0003-3326-3360)
- Brigid S. Boland (ORCID: https://orcid.org/0000-0002-5360-8816)
- Prerna Mathani
- Parambir S. Dulai (ORCID: https://orcid.org/0000-0002-9514-2321)
- William J. Sandborn (ORCID: https://orcid.org/0000-0002-3314-7960)
- Ariela Holmer (ORCID: https://orcid.org/0000-0003-0542-8439)
- Siddharth Singh (ORCID: https://orcid.org/0000-0002-2640-7269)
- Randy Longman
- Dana J. Lukin (ORCID: https://orcid.org/0000-0003-4581-2267)
- Niels Vande Casteele (ORCID: https://orcid.org/0000-0003-0854-0274)
- Robert Battat (ORCID: https://orcid.org/0000-0002-7421-9764)
- Mark A. Valasek (ORCID: https://orcid.org/0000-0003-1721-3451)
- Yushan Pan (ORCID: https://orcid.org/0000-0002-6595-1101)
- Amy Hemperly (ORCID: https://orcid.org/0000-0001-9841-222X)
- Paris Charilaou (ORCID: https://orcid.org/0000-0002-5512-4225)
- Lihui Qin
Institutions
- Northwestern University (US)
- University of Southern California (US)
- Cornell University (US)
- University of California San Diego (US)
- NYU Langone Health (US)
- Weill Cornell Medicine (US)
- Wake Forest University (US)
- Université de Montréal (CA)
Publication Details
- Journal
- Crohn s & Colitis 360
- Published
- 2024-10-01
- DOI
- https://doi.org/10.1093/crocol/otae052
- Primary Topic
- Inflammatory Bowel Disease
- Type
- article
- Field-Weighted Citation Impact
- 0.00