Metabolic profiling of the synthetic cannabinoid APP-CHMINACA (PX-3) as studied by in vitro and in vivo models
The outcomes of our study showed that the most suitable markers to detect the intake of APP-CHMINACA in blood and urine samples in the framework of toxicological, clinical and forensic investigations were the metabolite formed by the hydrolysis of the distal amide and its hydroxylated products.
Authors
- Sabrine Bilel (ORCID: https://orcid.org/0000-0003-1515-980X)
- Giorgia Corli (ORCID: https://orcid.org/0000-0002-2973-2446)
- Monica Mazzarino (ORCID: https://orcid.org/0000-0003-2036-930X)
- Matteo Marti (ORCID: https://orcid.org/0000-0001-8751-2882)
- Fabio De‐Giorgio (ORCID: https://orcid.org/0000-0001-7433-0924)
- Cristian Camuto (ORCID: https://orcid.org/0000-0001-7882-4841)
- Francesco Botrè (ORCID: https://orcid.org/0000-0001-5296-8126)
Institutions
- Università Cattolica del Sacro Cuore (IT)
- University of Ferrara (IT)
- Agostino Gemelli University Polyclinic (IT)
- Ghent University (BE)
- Federazione Medico Sportiva Italiana (IT)
- University of Lausanne (CH)
Publication Details
- Journal
- Forensic Toxicology
- Published
- 2024-11-22
- DOI
- https://doi.org/10.1007/s11419-024-00705-0
- Citations
- 1
- Primary Topic
- Forensic Toxicology and Drug Analysis
- Type
- article
- Field-Weighted Citation Impact
- 0.35
Funders
- Université de Lausanne