Estimation of physiological aging based on routine clinical biomarkers: a prospective cohort study in elderly Chinese and the UK Biobank
Our results highlight the potential of PAI and ΔPAI as integrative biomarkers to evaluate aging acceleration and facilitate the development of targeted intervention strategies for healthy aging.
Authors
- Xingjie Hao (ORCID: https://orcid.org/0000-0003-1535-9860)
- Ziwei Zhu (ORCID: https://orcid.org/0000-0002-3990-4774)
- Jingjing Lyu (ORCID: https://orcid.org/0000-0003-4420-6521)
- Chaolong Wang (ORCID: https://orcid.org/0000-0003-3945-1012)
- Shanshan Cheng (ORCID: https://orcid.org/0009-0004-0337-0426)
- Meian He (ORCID: https://orcid.org/0000-0002-2096-921X)
- Xiaomin Zhang (ORCID: https://orcid.org/0000-0003-3877-5242)
- Xiang Cheng (ORCID: https://orcid.org/0000-0001-9019-7246)
- Huan Guo
Institutions
- Union Hospital (HK)
- Huazhong University of Science and Technology (CN)
Publication Details
- Journal
- BMC Medicine
- Published
- 2024-11-22
- DOI
- https://doi.org/10.1186/s12916-024-03769-2
- Citations
- 10
- Primary Topic
- Birth, Development, and Health
- Type
- article
- Field-Weighted Citation Impact
- 11.09
Funders
- National Natural Science Foundation of China
- National Science and Technology Major Project
- Fundamental Research Funds for the Central Universities
- Science Fund for Distinguished Young Scholars of Hubei Province