Holliday junction recognition protein (HJURP) could reflect the clinical outcomes of lung adenocarcinoma patients, and impact the choice of precision therapy
HJURP is a pivotal biomarker for LUAD, consistently associated with poor prognosis and advanced disease stages. Its high expression correlates with specific genetic alterations and immune profiles, highlighting its potential as a therapeutic target. Future studies should validate these findings in larger cohorts.
Authors
- Xixi Gao (ORCID: https://orcid.org/0000-0002-2431-7710)
- Ming Zhang (ORCID: https://orcid.org/0000-0002-8709-055X)
- Yuejiao Sun
- Yingqing Zhang (ORCID: https://orcid.org/0000-0002-0395-8033)
Institutions
- Jiaxing University (CN)
Publication Details
- Journal
- Frontiers in Genetics
- Published
- 2024-11-22
- DOI
- https://doi.org/10.3389/fgene.2024.1475511
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00