Efficacy and tolerability of high-dose cefalexin 45 mg/kg/dose (maximum 1.5 g) three times daily in children with bone and joint infections
A reduced frequency dosing regimen using a high cefalexin dose of 45 mg/kg (maximum 1.5 g) three times daily is effective and well tolerated in most children with BJIs.
Authors
- Alison Boast (ORCID: https://orcid.org/0000-0002-9093-3992)
- Amanda Gwee (ORCID: https://orcid.org/0000-0003-4016-8986)
- Nigel Curtis (ORCID: https://orcid.org/0000-0003-3446-4594)
- Samar Hikmat
Institutions
- Royal Children's Hospital (AU)
- The University of Melbourne (AU)
- Murdoch Children's Research Institute (AU)
Publication Details
- Journal
- Journal of Antimicrobial Chemotherapy
- Published
- 2024-11-21
- DOI
- https://doi.org/10.1093/jac/dkae423
- Primary Topic
- Pneumocystis jirovecii pneumonia detection and treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Health and Medical Research Council