Exploring causal associations between interleukins, their receptors, and acute respiratory distress syndrome: a bidirectional-Mendelian Randomization study
This study elucidates the causal connections between specific interleukins, their receptors and ARDS, contributing significantly to the understanding of ARDS pathogenesis. These findings offer a foundation for further research and potential therapeutic interventions targeting these interleukins and receptors in ARDS management. The absence of reverse causation and pleiotropy, heterogeneity reinforces the robustness of these associations.
Authors
- Ji-chun Tang
- Jiawei Ma (ORCID: https://orcid.org/0000-0002-8625-5391)
- H. Fang
Institutions
- Jiangnan University (CN)
- Wuxi Fourth People's Hospital (CN)
- Wuxi No.2 People's Hospital (CN)
Publication Details
- Journal
- Frontiers in Genetics
- Published
- 2024-11-21
- DOI
- https://doi.org/10.3389/fgene.2024.1447661
- Citations
- 1
- Primary Topic
- Asthma and respiratory diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.33
Funders
- Natural Science Foundation of Xinjiang