Decreased expression of Syndecan‐ 1 (<scp>CD138</scp>) in the endometrium of adenomyosis patients suggests a potential pathogenetic role
For clinical significance in relation to our results, the investigated data showed that the downregulation of Syndecan-1 in adenomyotic patients in our study may suggest a role in promoting the invasiveness of endometriotic islands within the myometrium. However, further studies are still needed to understand the mechanistic contribution of Syndecan-1 to the pathogenesis of adenomyosis.
Authors
- Martin Götte (ORCID: https://orcid.org/0000-0003-2360-2496)
- Ariana Plasger (ORCID: https://orcid.org/0000-0003-4964-1389)
- Ludwig Kiesel (ORCID: https://orcid.org/0000-0002-7247-9247)
- Nourhan Hassan (ORCID: https://orcid.org/0000-0003-3189-8063)
- Andreas N. Schüring (ORCID: https://orcid.org/0000-0001-8276-1484)
- Mohamed Gamal Ibrahim (ORCID: https://orcid.org/0000-0001-6648-9281)
- Walid Shaalan (ORCID: https://orcid.org/0000-0002-2576-2269)
Institutions
- Cairo University (EG)
- Heidelberg University (DE)
- University of Münster (DE)
- University Hospital Heidelberg (DE)
- University Hospital Münster (DE)
- Kinderklinik Regensburg (DE)
Publication Details
- Journal
- Acta Obstetricia Et Gynecologica Scandinavica
- Published
- 2024-11-20
- DOI
- https://doi.org/10.1111/aogs.15012
- Citations
- 1
- Primary Topic
- Endometriosis Research and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.54
Funders
- Horizon 2020 Framework Programme
- Deutscher Akademischer Austausch Dienst Kairo