The mechanism of PDE7B inhibiting the development of hepatocellular carcinoma through oxidative stress
The research we conducted reveals that PDE7B, a gene with minimal levels of activity in hepatocellular carcinoma, possesses the capacity to inhibit the proliferation, invasion, and migration of HCC cells. PDE7B can impact the development of hepatocellular carcinoma by adjusting mechanisms related to oxidative stress.
Authors
- Linling Ju (ORCID: https://orcid.org/0000-0002-9541-0533)
- Jianghua Zhao (ORCID: https://orcid.org/0000-0001-7036-0800)
- Yunfeng Luo (ORCID: https://orcid.org/0000-0002-2503-3517)
- Jianguo Shao
- Lin Chen (ORCID: https://orcid.org/0000-0002-1108-4735)
- Huile Gao (ORCID: https://orcid.org/0000-0002-5355-7238)
Institutions
- Nantong University (CN)
- Affiliated Hospital of Nantong University (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2024-11-21
- DOI
- https://doi.org/10.3389/fimmu.2024.1469740
- Primary Topic
- Phosphodiesterase function and regulation
- Type
- article
- Field-Weighted Citation Impact
- 0.00