Evaluation of the patency rate and endothelialization of a poly-ε-caprolactone, nanofiber sheet-based vascular graft using a rat abdominal aortic implantation model

PCL grafts can exhibit autologous vessel-like regeneration; nonetheless, regarding patency, grafts made from rolled-up PCL nanofiber sheets have structural weaknesses. Further improvements are required to achieve a long-term and high patency rate for PCL grafts.

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Publication Details

Journal
Frontiers in Surgery
Published
2024-11-21
DOI
https://doi.org/10.3389/fsurg.2024.1464155
Primary Topic
Electrospun Nanofibers in Biomedical Applications
Type
article
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article

Evaluation of the patency rate and endothelialization of a poly-ε-caprolactone, nanofiber sheet-based vascular graft using a rat abdominal aortic implantation model

Patrícia Pranke, Kyohei Oyama, Naohiro Wakabayashi, Daikelly Iglesias Braghirolli et al.
Frontiers in Surgery
Electrospun Nanofibers in Biomedical Applications
article

Evaluation of the patency rate and endothelialization of a poly-ε-caprolactone, nanofiber sheet-based vascular graft using a rat abdominal aortic implantation model

Patrícia Pranke, Kyohei Oyama, Naohiro Wakabayashi, Daikelly Iglesias Braghirolli, Hiroyuki Kamiya, Yuta Kikuchi
article en

Abstract

PCL grafts can exhibit autologous vessel-like regeneration; nonetheless, regarding patency, grafts made from rolled-up PCL nanofiber sheets have structural weaknesses. Further improvements are required to achieve a long-term and high patency rate for PCL grafts.

Frontiers in SurgeryVol. 11
Universidade Federal do Rio Grande (BR), Universidade Federal do Rio Grande do Sul (BR), Asahikawa Medical University (JP)
Openalex Percentile: Top 90%
Electrospun Nanofibers in Biomedical Applications
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