New 4-amino-3-chloro benzoate ester derivatives as EGFR inhibitors: synthesis, in silico and biological analyses
The results of this study show that compound <b>N5a</b> is a promising cytotoxic compound that inhibits the tyrosine kinase activity of EGFR.
Authors
- Ammar Kubba (ORCID: https://orcid.org/0000-0002-4915-417X)
- Lubna H. Tahtamouni (ORCID: https://orcid.org/0000-0001-8024-1944)
- Nedaa A. Abd Al Rahim
- Salem R. Yasin (ORCID: https://orcid.org/0000-0002-0251-1192)
- Abdulrahman M. Saleh (ORCID: https://orcid.org/0000-0002-5153-7399)
- Mai F. AlSakhen (ORCID: https://orcid.org/0009-0002-0213-2683)
Institutions
- University of Baghdad (IQ)
- Cairo University (EG)
- Hashemite University (JO)
- Colorado State University (US)
Publication Details
- Journal
- Future Medicinal Chemistry
- Published
- 2024-11-20
- DOI
- https://doi.org/10.1080/17568919.2024.2431478
- Citations
- 4
- Primary Topic
- HER2/EGFR in Cancer Research
- Type
- article
- Field-Weighted Citation Impact
- 1.13
Funders
- University of Baghdad
- Hashemite University