Cyclosporine successfully treats steroid-resistant checkpoint inhibitor-related pneumonitis: a case report
This marks the first instance of effectively managing steroid-resistant CIP through the combined use of cyclosporine and corticosteroids. Presently, cases of steroid-resistant CIP remain infrequent, necessitating vigilant and meticulous monitoring within clinical settings. Notably, there exists no distinct guideline specifying a singular agent for rescuing patients unresponsive to corticosteroid therapy. Therefore, cyclosporine emerges as a promising and efficacious treatment alternative for individuals unresponsive to corticosteroid intervention in the context of CIP.
Authors
- Ru Li (ORCID: https://orcid.org/0000-0001-5398-3168)
- Wenhui Guan
- Wenwei Mo
- Jiaxi Deng
- Xinqing Lin
- Ni Sun
- Haiyi Deng
- Chengzhi Zhou (ORCID: https://orcid.org/0000-0002-1758-0035)
- Minjuan Hu
Institutions
- First Affiliated Hospital of Guangzhou Medical University (CN)
- State Key Laboratory of Respiratory Disease (CN)
- Guangzhou Medical University (CN)
Publication Details
- Journal
- BMC Pulmonary Medicine
- Published
- 2024-11-21
- DOI
- https://doi.org/10.1186/s12890-024-03258-5
- Citations
- 3
- Primary Topic
- Cancer Immunotherapy and Biomarkers
- Type
- article
- Field-Weighted Citation Impact
- 0.85
Funders
- Guangzhou Municipal Health and Family Planning Commission