Cyclosporine successfully treats steroid-resistant checkpoint inhibitor-related pneumonitis: a case report

This marks the first instance of effectively managing steroid-resistant CIP through the combined use of cyclosporine and corticosteroids. Presently, cases of steroid-resistant CIP remain infrequent, necessitating vigilant and meticulous monitoring within clinical settings. Notably, there exists no distinct guideline specifying a singular agent for rescuing patients unresponsive to corticosteroid therapy. Therefore, cyclosporine emerges as a promising and efficacious treatment alternative for individuals unresponsive to corticosteroid intervention in the context of CIP.

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Publication Details

Journal
BMC Pulmonary Medicine
Published
2024-11-21
DOI
https://doi.org/10.1186/s12890-024-03258-5
Citations
3
Primary Topic
Cancer Immunotherapy and Biomarkers
Type
article
Field-Weighted Citation Impact
0.85

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article

Cyclosporine successfully treats steroid-resistant checkpoint inhibitor-related pneumonitis: a case report

Ru Li, Wenhui Guan, Wenwei Mo, Jiaxi Deng et al.
3 citations
BMC Pulmonary Medicine
Cancer Immunotherapy and Biomarkers
0.85
article

Cyclosporine successfully treats steroid-resistant checkpoint inhibitor-related pneumonitis: a case report

Ru Li, Wenhui Guan, Wenwei Mo, Jiaxi Deng, Xinqing Lin, Ni Sun, Haiyi Deng, Chengzhi Zhou, Minjuan Hu
article en
3 citations

Abstract

This marks the first instance of effectively managing steroid-resistant CIP through the combined use of cyclosporine and corticosteroids. Presently, cases of steroid-resistant CIP remain infrequent, necessitating vigilant and meticulous monitoring within clinical settings. Notably, there exists no distinct guideline specifying a singular agent for rescuing patients unresponsive to corticosteroid therapy. Therefore, cyclosporine emerges as a promising and efficacious treatment alternative for individuals unresponsive to corticosteroid intervention in the context of CIP.

BMC Pulmonary MedicineVol. 24(1)
First Affiliated Hospital of Guangzhou Medical University (CN), State Key Laboratory of Respiratory Disease (CN), Guangzhou Medical University (CN)
Guangzhou Municipal Health and Family Planning Commission
Openalex Percentile: Top 21%
Cancer Immunotherapy and Biomarkers
0.85
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Cyclosporine successfully treats steroid-resistant checkpoint inhibitor-related pneumonitis: a case report — Ru Li, Wenhui Guan, et al. · BMC Pulmonary Medicine (2024) | TGRS Research Map | TGRS