Identification of Macrophage-Associated Novel Drug Targets in Atherosclerosis Based on Integrated Transcriptome Features
CD86, LILRB2, and IRF8 are highly expressed in foam cell samples, with CD86 forming hydrogen bonds with several AS drugs, indicating CD86 as a promising target for AS treatment.
Authors
- Jixin Zhi
- Sida Qin (ORCID: https://orcid.org/0009-0003-0454-0493)
- Xiaohui Zhang (ORCID: https://orcid.org/0000-0003-0245-6792)
- Jingzhi Wang (ORCID: https://orcid.org/0000-0001-6439-9805)
Institutions
- Harbin Medical University (CN)
- Fourth Affiliated Hospital of Harbin Medical University (CN)
- First Affiliated Hospital of Harbin Medical University (CN)
Publication Details
- Journal
- Journal of Chemical Information and Modeling
- Published
- 2024-11-21
- DOI
- https://doi.org/10.1021/acs.jcim.4c01558
- Citations
- 3
- Primary Topic
- Atherosclerosis and Cardiovascular Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.72