Transcriptomics of tissue exosomes to investigate miR-195-5p’s amelioration of endometrial fibrosis via the YAP-Smad7 pathway: an animal study
Differential expression of miR-195-5p in tissue exosomes can reduce ECM deposition and myofibroblast transdifferentiation, improving endometrial fibrosis by regulating the YAP-Smad7 pathway in the Hippo signaling cascade.
Authors
- Yan‐Chuan Shi (ORCID: https://orcid.org/0000-0002-8368-6735)
- Qiao-yi Huang
- Shu Lin (ORCID: https://orcid.org/0000-0002-4239-2028)
- Jinxiang Wu (ORCID: https://orcid.org/0000-0002-5231-7603)
- Jia‐ming Chen
- Qiyang Shi (ORCID: https://orcid.org/0000-0002-7976-2029)
- Ling‐tao Zheng
- Weihong Chen (ORCID: https://orcid.org/0000-0001-8689-7311)
- Hui‐jie You
Institutions
- Fujian Medical University (CN)
- Garvan Institute of Medical Research (AU)
- St Vincent's Clinic (AU)
- Second Affiliated Hospital of Fujian Medical University (CN)
Publication Details
- Journal
- Journal of Translational Medicine
- Published
- 2024-11-21
- DOI
- https://doi.org/10.1186/s12967-024-05871-8
- Citations
- 3
- Primary Topic
- Gynecological conditions and treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.75
Funders
- Fujian Provincial Health Technology Project