Cyclometalated Ruthenium-Complex-Catalyzed Selective Oxidation of Olefins to Carbonyls

Cyclometalated ruthenium(II)-complex-catalyzed selective oxidative scission of olefins to carbonyls is described. A strong C-donor ligand, paired with a rigid backbone and redox activity of ruthenium, provided high catalytic activity and a long lifetime for olefin oxidation. The catalyst tolerates numerous functional groups and applies to challenging biomass-, natural-product-, sugar-, amino-acid-, and fatty-acid-derived substrates.