Are Chronic lymphocytic leukemia blood parameters differing from Other leukemias subtypes

Background: Adults widely acknowledge CLL as a prevalent lymphoproliferative disease, a hematological malignancy. Thus, the objective of this study was to assess potential differences in blood parameters among CLL and other subtypes of leukemia. Methodology: The current study utilized lymphoma data acquired from El-Obeid Oncology Center. The document included data on lymphoma patients diagnosed between January 2018 and January 2020. The sample included a total of one hundred patients, of which sixty-one had CLL and forty-nine did not. The traditional BM aspiration diagnosis for the patient was lymphoma. Results: Within this series, CLL was the most prevalent form of cancer, followed by CML, NHL, MM, HL, and various other types, making up 61%, 17%, 11%, 6%, and 3% of cases, respectively. All cases of CLL, MM, and NHL exhibited BM hypercellularity. Megakaryopoiesis was not observed in ten cases, which consisted of eight (80%) CLL patients and two (20%) MM patients. We observed megakaryopoiesis in 43 instances, with 60.5% of the cases being CLL and 30.2% being CML. There were only two instances where CLL showed a decrease in megakaryopoiesis. We found 34 patients with depressed erythropoiesis. This included CLL in 59% of cases, CML in 26.5% of cases, and MM in 8.8% of cases. Conclusion: CLL demonstrates a unique set of hematological parameters when compared to other blood malignancies. CML demonstrates a pattern that is similar to CLL in different hematological parameters, such as the overall count of white blood cells.