One-pot synthesis of lactones from ketoacids involving microwave heating and sodium borohydride: application in biomass conversion
A metal-free one-pot cascade method involving NaBH<sub>4</sub> and microwave (MW)-heating efficiently synthesized lactones, including the industrially significant γ-valerolactone at 90% yield. The process directly converts methyl levulinate, succinic acid and a wide range of aliphatic and aromatic ketoacids, in H<sub>2</sub>O or THF, proceeding <i>via</i> reduction, COOH proton exchange, cyclization, and dehydration, showing promise for biomass conversion.
Authors
- Arun Kumar Solanki
- Raina Sharma (ORCID: https://orcid.org/0000-0002-4986-7188)
- Govindasamy Jayamurugan (ORCID: https://orcid.org/0000-0001-9870-5209)
Institutions
- Institute of Nano Science and Technology
Publication Details
- Journal
- Chemical Communications
- Published
- 2024-11-21
- DOI
- https://doi.org/10.1039/d4cc05194g
- Citations
- 2
- Primary Topic
- Catalysis for Biomass Conversion
- Type
- article
- Field-Weighted Citation Impact
- 0.37
Funders
- Department of Biotechnology, Ministry of Science and Technology, India
- Science and Engineering Research Board