Ficolin-1 ameliorates pulmonary fibrosis via directly binding to TGF-β1
Ficolin-1 inhibits pulmonary fibrosis by directly binding to the key profibrogenic factor TGF-β1, marking it as a potential target for therapy in the treatment of fibrotic lung diseases.
Authors
- Yingwei Zhu
- Yimin Mao (ORCID: https://orcid.org/0000-0002-0709-4236)
- Kun Tang (ORCID: https://orcid.org/0000-0002-8418-143X)
- Jianping Zhao
- Tongsheng Wang (ORCID: https://orcid.org/0000-0003-0840-407X)
- Pengfei Gao (ORCID: https://orcid.org/0000-0002-0269-0127)
- Wei Wang (ORCID: https://orcid.org/0000-0003-1005-059X)
- Yanjiao Lu (ORCID: https://orcid.org/0000-0002-8601-6972)
Institutions
- Sun Yat-sen University (CN)
- The First Affiliated Hospital, Sun Yat-sen University (CN)
- First Affiliated Hospital of Henan University of Science and Technology (CN)
- Tongji Hospital (CN)
- Huazhong University of Science and Technology (CN)
Publication Details
- Journal
- Journal of Translational Medicine
- Published
- 2024-11-21
- DOI
- https://doi.org/10.1186/s12967-024-05894-1
- Citations
- 4
- Primary Topic
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Type
- article
- Field-Weighted Citation Impact
- 1.68
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Henan Province
- Henan Provincial Science and Technology Research Project