Dissecting the pathogenic effects of smoking in blood DNA methylation on allergic diseases
Our study has highlighted the associations between smoking behaviors and allergic diseases in the genetic and epigenetic landscape, notably asthma. We identified several DNA methylation-related CpG sites, such as cg03689048 (BAT3), cg17272563 (PRRT1), and cg20069688 (STK19), which demonstrate cross-allergic potential and reverse causal relationships.
Authors
- Jinyang Wen
- Jing Ye (ORCID: https://orcid.org/0000-0002-9471-3321)
- Binxiang Tang
- Qing Luo (ORCID: https://orcid.org/0000-0001-7559-5174)
- Fan Jiang (ORCID: https://orcid.org/0000-0002-0023-3002)
- Wei Wan (ORCID: https://orcid.org/0000-0001-9462-5615)
- Junhao Tu (ORCID: https://orcid.org/0000-0002-1306-0323)
Institutions
- Nanchang University (CN)
- National University of Singapore (SG)
- First Affiliated Hospital of Jiangxi Medical College (CN)
- Second Affiliated Hospital of Nanchang University (CN)
- National University Health System (SG)
- Tongji Hospital (CN)
- Huazhong University of Science and Technology (CN)
Publication Details
- Journal
- World Allergy Organization Journal
- Published
- 2024-11-21
- DOI
- https://doi.org/10.1016/j.waojou.2024.100995
- Citations
- 4
- Primary Topic
- Asthma and respiratory diseases
- Type
- article
- Field-Weighted Citation Impact
- 1.31
Funders
- National Natural Science Foundation of China