Pharmacological Evaluation of the Traditional Brazilian Medicinal Plant Monteverdia ilicifolia in Gastroesophageal Reflux Disease: Preliminary Results of a Randomized Double-Blind Controlled Clinical Trial
Our results suggest that capsules with a standardized dry extract from the leaves of <i>M. ilicifolia</i> at a dosage of 400 or 860 mg are non-inferior to omeprazole, a proton pump inhibitor.
Authors
- Sara Elis Bianchi (ORCID: https://orcid.org/0000-0002-3759-6587)
- Marcelo Rodrigues Gonçalves (ORCID: https://orcid.org/0000-0001-8516-8547)
- Matheus de Freitas Silva (ORCID: https://orcid.org/0000-0001-9001-2758)
- Gabriela de Carvalho Meirelles (ORCID: https://orcid.org/0000-0001-7533-0440)
- Caroline Dani (ORCID: https://orcid.org/0000-0003-0046-7148)
- Rebeca Vargas Antunes Schunck
- Valquíria Linck Bassani (ORCID: https://orcid.org/0000-0001-9525-5855)
- Leonardo Vieira Targa (ORCID: https://orcid.org/0000-0002-6715-7817)
- Giana Blume Corssac
- Ionara Rodrigues Siqueira (ORCID: https://orcid.org/0000-0002-4460-0978)
- Marcelo Aragão Moraes (ORCID: https://orcid.org/0009-0002-0162-5443)
Institutions
- Universidade Federal do Rio Grande do Sul (BR)
- Universidade de Caxias do Sul (BR)
Publication Details
- Journal
- Pharmaceuticals
- Published
- 2024-11-20
- DOI
- https://doi.org/10.3390/ph17111559
- Citations
- 1
- Primary Topic
- Gastroesophageal reflux and treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.46
Funders
- Conselho Nacional de Desenvolvimento Científico e Tecnológico
- Ministério da Saúde