Assessment of systemic reaction to inflammation induced by photodynamic therapy in cervical intraepithelial neoplasia
One of the mechanisms of PDT`s antitumor and antiviral action is the development of acute inflammation in response to cytotoxic action on cells and vascular response in the form of pathological area devascularization. Such reactive inflammation activates all parts of the immune system. Changes on day 5 post-PDT in inflammatory parameters in CBC and IL-1, IL-6 and TNF-α markers correlate with the clinical picture of the post-photodynamic effect.
Authors
- Т. Г. Гришачева (ORCID: https://orcid.org/0000-0002-9515-914X)
- Alexander Dushkin (ORCID: https://orcid.org/0000-0002-8013-5276)
- M. S. Afanasiev (ORCID: https://orcid.org/0000-0002-5860-4152)
- Nasrulla Shanazarov (ORCID: https://orcid.org/0000-0002-2976-259X)
- Balkenzhe Imankulova (ORCID: https://orcid.org/0000-0001-8124-5517)
- S. B. Smailova (ORCID: https://orcid.org/0000-0002-2799-9227)
- Alisher Aitkaliyev (ORCID: https://orcid.org/0009-0002-9624-2663)
- Zhanara Salmaganbetova
Institutions
- Sechenov University (RU)
- First Pavlov State Medical University of St. Petersburg (RU)
- Astana Medical University (KZ)
- Global Health Research Center of Central Asia (KZ)
- Moscow City Oncology Hospital №62 (RU)
Publication Details
- Journal
- Photodiagnosis and Photodynamic Therapy
- Published
- 2024-11-21
- DOI
- https://doi.org/10.1016/j.pdpdt.2024.104416
- Citations
- 4
- Primary Topic
- Photodynamic Therapy Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 1.68
Funders
- Ministry of Education and Science of the Republic of Kazakhstan