A phase II study evaluating safety and efficacy of niraparib in patients with previously treated homologous recombination defective metastatic esophageal/gastroesophageal junction/proximal gastric adenocarcinoma

In patients with metastatic EAC, single agent niraparib as second line therapy is not an effective option.

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Publication Details

Journal
Frontiers in Oncology
Published
2024-11-21
DOI
https://doi.org/10.3389/fonc.2024.1435056
Citations
3
Primary Topic
PARP inhibition in cancer therapy
Type
article
Field-Weighted Citation Impact
0.85
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article

A phase II study evaluating safety and efficacy of niraparib in patients with previously treated homologous recombination defective metastatic esophageal/gastroesophageal junction/proximal gastric adenocarcinoma

Bryan P. Schneider, Susan M. Perkins, Heather Burney, Hirva Mamdani et al.
3 citations
Frontiers in Oncology
PARP inhibition in cancer therapy
0.85
article

A phase II study evaluating safety and efficacy of niraparib in patients with previously treated homologous recombination defective metastatic esophageal/gastroesophageal junction/proximal gastric adenocarcinoma

Bryan P. Schneider, Susan M. Perkins, Heather Burney, Hirva Mamdani, Christos Fountzilas, Shadia I. Jalal, Ahmed Bilal Khalid, Christopher A. Fausel
article en
3 citations

Abstract

In patients with metastatic EAC, single agent niraparib as second line therapy is not an effective option.

Frontiers in OncologyVol. 14
Indiana University Health (US), Roswell Park Comprehensive Cancer Center (US), The Barbara Ann Karmanos Cancer Institute (US), Indiana University School of Medicine, Indiana University – Purdue University Indianapolis (US)
Good health and well-being
Openalex Percentile: Top 22%
PARP inhibition in cancer therapy
0.85
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A phase II study evaluating safety and efficacy of niraparib in patients with previously treated homologous recombination defective metastatic esophageal/gastroesophageal junction/proximal gastric adenocarcinoma — Bryan P. Schneider, Susan M. Perkins, et al. · Frontiers in Oncology (2024) | TGRS Research Map | TGRS