A machine learning model revealed that exosome small RNAs may participate in the development of breast cancer through the chemokine signaling pathway
The combination of six plasma exosome small RNAs has good prognostic value for women with positive breast cancer by imaging screening. The chemokine signaling pathway may be involved in the early stage of breast cancer. It is worth further exploring whether small RNAs mediate chemokine signaling pathways in the pathogenesis of breast cancer through the delivery of exosomes.
Authors
- Ji‐Ye Yin (ORCID: https://orcid.org/0000-0002-1244-5045)
- Junluan Mo
- Xiongshun Liang
- Zhaoqian Liu (ORCID: https://orcid.org/0000-0003-0428-3928)
- Wen‐Xu Hong (ORCID: https://orcid.org/0000-0003-0260-1099)
- Lin Lei (ORCID: https://orcid.org/0000-0001-6687-6898)
- Xi Li (ORCID: https://orcid.org/0000-0002-4713-2612)
- Hong‐Hao Zhou (ORCID: https://orcid.org/0000-0003-4252-3304)
- Peng Ji (ORCID: https://orcid.org/0000-0002-5733-0604)
Institutions
- Central South University (CN)
- National Clinical Research Center for Digestive Diseases (CN)
- National Clinical Research (US)
- PharmacoGenetics (China) (CN)
- Xiangya Hospital Central South University (CN)
- Shenzhen Nanshan Center for Chronic Disease Control (CN)
Publication Details
- Journal
- BMC Cancer
- Published
- 2024-11-21
- DOI
- https://doi.org/10.1186/s12885-024-13173-x
- Citations
- 2
- Primary Topic
- MicroRNA in disease regulation
- Type
- article
- Field-Weighted Citation Impact
- 0.57
Funders
- National Natural Science Foundation of China
- Sanming Project of Medicine in Shenzhen