Abnormal hypothalamic functional connectivity and serum arousal-promoting neurotransmitters in insomnia disorder patients: a pilot study
ID patients exhibited aberrant FC in brain regions related to sleep-wake regulation, particularly involving the default mode network and anterior cingulate cortex, which may correlate with the peripheral levels of histamine. These findings contribute to our understanding of the potential neuroimaging and neurohumoral mechanism underlying ID patients.
Authors
- Yixian Cai
- Zhenye Luo (ORCID: https://orcid.org/0000-0002-7118-2855)
- Jingjing Lin (ORCID: https://orcid.org/0000-0003-0043-6560)
- Liting Chen (ORCID: https://orcid.org/0000-0002-7786-1226)
- Fan Mei (ORCID: https://orcid.org/0000-0003-4285-2749)
- Jiyang Pan (ORCID: https://orcid.org/0009-0003-5082-2985)
- Yaxi Liu (ORCID: https://orcid.org/0000-0002-3261-829X)
- Xian Shi (ORCID: https://orcid.org/0000-0001-5796-4116)
- Zhiyun Yang
Institutions
- Soochow University (CN)
- First Affiliated Hospital of Soochow University (CN)
- First Affiliated Hospital of Jinan University (CN)
Publication Details
- Journal
- PeerJ
- Published
- 2024-11-21
- DOI
- https://doi.org/10.7717/peerj.18540
- Citations
- 3
- Primary Topic
- Sleep and Wakefulness Research
- Type
- article
- Field-Weighted Citation Impact
- 1.03
Funders
- National Key Research and Development Program of China