(<scp>TTTCA</scp>)exp Drives the Genotype–Phenotype Correlation and Genetic Anticipation in <scp>FCMTE1</scp>
The (TTTCA)exp insertion serves as the length-dependent pathogenic component within the two-motif repeat expansion. Its differential expanding nature during parental transmissions is highly associated with the genetic anticipation in FCMTE1. © 2024 International Parkinson and Movement Disorder Society.
Authors
- Shuang Wang (ORCID: https://orcid.org/0000-0001-5211-9036)
- Lebo Wang
- Yao Ding (ORCID: https://orcid.org/0000-0002-0599-8872)
- Ben Hu (ORCID: https://orcid.org/0000-0001-5451-1736)
- Dehao Yang (ORCID: https://orcid.org/0000-0002-4129-9761)
- Zhidong Cen (ORCID: https://orcid.org/0000-0003-3155-5781)
- Yiling Elaine Chen (ORCID: https://orcid.org/0000-0001-7259-2787)
- Yixin Kang (ORCID: https://orcid.org/0000-0002-1131-6823)
- Huijun Yu (ORCID: https://orcid.org/0000-0001-8108-4434)
- Haibin Xia (ORCID: https://orcid.org/0000-0002-2038-5759)
- Nan Jin (ORCID: https://orcid.org/0000-0003-0297-1305)
- Sheng Wu (ORCID: https://orcid.org/0000-0002-2024-2432)
- Wei Luo (ORCID: https://orcid.org/0000-0001-6951-7698)
- Peng Liu (ORCID: https://orcid.org/0000-0001-8824-3370)
- Miao Chen (ORCID: https://orcid.org/0000-0002-1424-9160)
- Haotian Wang (ORCID: https://orcid.org/0000-0002-7677-8930)
- Fan Zhang (ORCID: https://orcid.org/0000-0002-2715-5657)
- Bo Wang (ORCID: https://orcid.org/0000-0002-7150-237X)
- Fei Xie (ORCID: https://orcid.org/0000-0003-3674-8216)
- Xinhui Chen (ORCID: https://orcid.org/0009-0009-9940-9327)
- Aisi Fu (ORCID: https://orcid.org/0000-0002-3539-8093)
- Zhiyuan Ouyang (ORCID: https://orcid.org/0000-0003-0204-857X)
- Junfeng Ji (ORCID: https://orcid.org/0000-0001-5040-1863)
Institutions
- Wenzhou Medical University (CN)
- Sir Run Run Shaw Hospital (CN)
- Wuhan University (CN)
- Zhongnan Hospital of Wuhan University (CN)
- Third People's Hospital of Hangzhou (CN)
- Taizhou Central Hospital (CN)
- Second Affiliated Hospital of Zhejiang University (CN)
- Zhejiang University (CN)
- Taizhou University (CN)
Publication Details
- Journal
- Movement Disorders
- Published
- 2024-11-21
- DOI
- https://doi.org/10.1002/mds.30057
- Citations
- 1
- Primary Topic
- Genetics and Neurodevelopmental Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.55
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Zhejiang Province
- Science and Technology Program of Zhejiang Province