The functional TNF-α−308G > a single-nucleotide polymorphism (rs1800629): association with the predictive indices of breast cancer carcinogenesis
This research is the first to correlate TNF-α<sup>-308</sup>G > A (rs1800629) SNP in Egyptian BC patients. The A allele, GA & AA genotypes, and the Overdominant model of the TNF-α<sup>-308</sup>G > A gene variants were recorded as prognostic risk factors for BC carcinogenesis.
Authors
- Sherif Refaat (ORCID: https://orcid.org/0000-0002-9198-4900)
- Zeinab R. Attia (ORCID: https://orcid.org/0000-0003-1907-5419)
- Sahar Hamed (ORCID: https://orcid.org/0000-0002-6847-6553)
- Hanan E. Al-Rashidi
- Rania A. Abd El Azeem (ORCID: https://orcid.org/0000-0002-8578-6537)
- Walaa E. Nouh
Institutions
- Mansoura University (EG)
- Taibah University (SA)
- Children's Hospital Mansoura University (EG)
- University of Hafr Al-Batin (SA)
Publication Details
- Journal
- Breast Cancer Research and Treatment
- Published
- 2024-11-21
- DOI
- https://doi.org/10.1007/s10549-024-07536-y
- Primary Topic
- Cytokine Signaling Pathways and Interactions
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Mansoura University