Wnt signaling aberrant activation drives ameloblastoma invasion and recurrence: bioinformatics and in vitro insights

This study reveals the critical role of aberrant Wnt signaling activation in AM proliferation and migration, identifying it as a key driver of AM invasion and recurrence. The findings provide new insights into the mechanisms underlying AM invasion and recurrence, laying the foundation for developing novel therapeutic strategies.

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Publication Details

Journal
BMC Oral Health
Published
2024-11-21
DOI
https://doi.org/10.1186/s12903-024-05003-0
Primary Topic
Oral and Maxillofacial Pathology
Type
article
Field-Weighted Citation Impact
0.00

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article

Wnt signaling aberrant activation drives ameloblastoma invasion and recurrence: bioinformatics and in vitro insights

Yemei Qian, Hongrong Zhang, Weihong Wang, Jing Li et al.
BMC Oral Health
Oral and Maxillofacial Pathology
article

Wnt signaling aberrant activation drives ameloblastoma invasion and recurrence: bioinformatics and in vitro insights

Yemei Qian, Hongrong Zhang, Weihong Wang, Jing Li, You Qin, Jian Zhang, Liangchong Huang
article en

Abstract

This study reveals the critical role of aberrant Wnt signaling activation in AM proliferation and migration, identifying it as a key driver of AM invasion and recurrence. The findings provide new insights into the mechanisms underlying AM invasion and recurrence, laying the foundation for developing novel therapeutic strategies.

BMC Oral HealthVol. 24(1)
Yunnan University (CN), Kunming Medical University (CN), Stomatology Hospital (CN)
National Natural Science Foundation of China
Zero hunger
Openalex Percentile: Top 68%
Oral and Maxillofacial Pathology
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