ADAR1 enhances tumor proliferation and radioresistance in non-small cell lung cancer by interacting with Rad18
Our results revealed the role of ADAR1 in cooperation with Rad18 in modulating oncogenesis and radioresistance in NSCLC for the first time, and suggested the therapeutic potential of targeting ADAR1 in overcoming radioresistance.
Authors
- Yulan Zeng (ORCID: https://orcid.org/0000-0002-6415-1794)
- Xiaohua Hong (ORCID: https://orcid.org/0000-0002-5294-7445)
- Fei Gu (ORCID: https://orcid.org/0000-0002-7725-3909)
- Kai Zhang (ORCID: https://orcid.org/0009-0009-7164-9556)
- Yuting Liu (ORCID: https://orcid.org/0000-0001-9175-514X)
- Li Liu (ORCID: https://orcid.org/0000-0002-3275-2499)
- Juanjuan Wang (ORCID: https://orcid.org/0000-0003-2450-7554)
- Chang Li (ORCID: https://orcid.org/0000-0002-4368-4276)
- Chen Tian (ORCID: https://orcid.org/0000-0003-2710-7628)
- Yue Hu (ORCID: https://orcid.org/0000-0002-9814-0233)
- Hongjie Fan (ORCID: https://orcid.org/0000-0002-0211-2888)
- Jiaqi Gao (ORCID: https://orcid.org/0000-0003-1162-8269)
Institutions
- Union Hospital (HK)
- Huazhong University of Science and Technology (CN)
Publication Details
- Journal
- Cellular Oncology
- Published
- 2024-11-21
- DOI
- https://doi.org/10.1007/s13402-024-01012-x
- Citations
- 4
- Primary Topic
- RNA regulation and disease
- Type
- article
- Field-Weighted Citation Impact
- 0.94
Funders
- National Natural Science Foundation of China