Simplifying Mitral Valve Repair with Novel Premeasured Chordal Loops

<b>Background:</b> The "respect" approach to surgical mitral valve repair, which involves implanting artificial neochordae, is gaining increased adoption. Surgeons are possibly prone to error in the manual construction of neochordae, which can lead to prolonged cross-clamp times. Novel systems such as Chord-X Pre-Measured Loops (On-X Life Technologies, Inc., Austin, TX, USA) eliminate the need for manual neochordae construction, potentially simplifying the mitral repair procedure. However, clinical data on its use are currently limited to a small publication. <b>Methods</b>: We conducted a retrospective cohort study to evaluate the use of Chord-X loops in 40 consecutive patients who underwent surgery in Geelong, Victoria, Australia, between May 2020 and February 2024. Three surgeons participated in this study. <b>Results</b>: All patients were referred for severe mitral valve regurgitation secondary to myxomatous degeneration, with P2 prolapse being the most common pathology. Chord-X Pre-Measured Loops effectively corrected a variety of leaflet pathologies, including bi-leaflet disease, with a single set of loops sufficing in most patients. Intraoperative and follow-up echocardiographic assessments revealed no greater than mild mitral regurgitation in any patient, with 75% exhibiting no or trace mitral regurgitation. <b>Conclusions</b>: The Chord-X Pre-Measured Loops system demonstrated safety, efficacy, and reproducibility across all patients. Surgeons were able to easily adopt this technology without requiring additional training. We believe this technology offers a safe option for surgeons performing low-volume mitral repair surgeries.

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Publication Details

Journal
Journal of Clinical Medicine
Published
2024-11-21
DOI
https://doi.org/10.3390/jcm13237029
Primary Topic
Cardiac Valve Diseases and Treatments
Type
article
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article

Simplifying Mitral Valve Repair with Novel Premeasured Chordal Loops

Cheng-Hon Yap, Michael Rowland, Manoras Mathew Chengalath, Daniel Shell et al.
1 links
Journal of Clinical Medicine
Cardiac Valve Diseases and Treatments
article

Simplifying Mitral Valve Repair with Novel Premeasured Chordal Loops

Cheng-Hon Yap, Michael Rowland, Manoras Mathew Chengalath, Daniel Shell, Natcha Bunwatcharaphan, Michael Seitz
article en

Abstract

<b>Background:</b> The "respect" approach to surgical mitral valve repair, which involves implanting artificial neochordae, is gaining increased adoption. Surgeons are possibly prone to error in the manual construction of neochordae, which can lead to prolonged cross-clamp times. Novel systems such as Chord-X Pre-Measured Loops (On-X Life Technologies, Inc., Austin, TX, USA) eliminate the need for manual neochordae construction, potentially simplifying the mitral repair procedure. However, clinical data on its use are currently limited to a small publication. <b>Methods</b>: We conducted a retrospective cohort study to evaluate the use of Chord-X loops in 40 consecutive patients who underwent surgery in Geelong, Victoria, Australia, between May 2020 and February 2024. Three surgeons participated in this study. <b>Results</b>: All patients were referred for severe mitral valve regurgitation secondary to myxomatous degeneration, with P2 prolapse being the most common pathology. Chord-X Pre-Measured Loops effectively corrected a variety of leaflet pathologies, including bi-leaflet disease, with a single set of loops sufficing in most patients. Intraoperative and follow-up echocardiographic assessments revealed no greater than mild mitral regurgitation in any patient, with 75% exhibiting no or trace mitral regurgitation. <b>Conclusions</b>: The Chord-X Pre-Measured Loops system demonstrated safety, efficacy, and reproducibility across all patients. Surgeons were able to easily adopt this technology without requiring additional training. We believe this technology offers a safe option for surgeons performing low-volume mitral repair surgeries.

Journal of Clinical MedicineVol. 13(23)
Barwon Health (AU), Deakin University (AU), Monash University (AU)
Responsible consumption and production
Openalex Percentile: Top 61%
Cardiac Valve Diseases and Treatments
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