Enhanced Ocular Bioavailability and Prolonged Duration via Hydrophilic Surface Nanocomposite Vesicles for Topical Drug Administration
The CPP-modified PLGA nanoparticles provide an effective and innovative solution for ocular drug delivery, offering improved bioavailability, prolonged retention, and enhanced drug penetration, thereby overcoming the challenges of traditional intraocular drug administration methods.
Authors
- Zhenmiao Qin (ORCID: https://orcid.org/0000-0003-1353-0900)
- Sa Huang
- Zhijiong Wang
- Junfeng Ban (ORCID: https://orcid.org/0000-0001-7334-9375)
- Fan Li (ORCID: https://orcid.org/0000-0003-2584-3162)
- Yuan Xu
- Yingyao Luo
Institutions
- Guilin Medical University (CN)
- Guangdong Pharmaceutical University (CN)
- Guangdong Laboratory Animals Monitoring Institute (CN)
- Innovation Team (China) (HK)
- Hainan Medical University (CN)
Publication Details
- Journal
- Pharmaceutics
- Published
- 2024-11-21
- DOI
- https://doi.org/10.3390/pharmaceutics16121496
- Citations
- 2
- Primary Topic
- Advanced Drug Delivery Systems
- Type
- article
- Field-Weighted Citation Impact
- 0.42