Association of intra-articular injection and knee arthroscopy prior to primary knee replacement with the timing and outcomes of surgery: Retrospective cohort study using data from the Clinical Practice Research Datalink GOLD database

Steroid injection and knee arthroscopy prior to primary knee replacement are each associated with worse outcomes. The observed association of lower mortality risk is suggestive of confounding by indication. The observed associations in this study could be used to inform shared decision making with patients on the treatment pathway for knee osteoarthritis.

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Publication Details

Journal
PLoS ONE
Published
2024-11-21
DOI
https://doi.org/10.1371/journal.pone.0311947
Primary Topic
Total Knee Arthroplasty Outcomes
Type
article
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article

Association of intra-articular injection and knee arthroscopy prior to primary knee replacement with the timing and outcomes of surgery: Retrospective cohort study using data from the Clinical Practice Research Datalink GOLD database

Antonella Delmestri, John Broomfield, Andrew Judge, Setor K. Kunutsor et al.
PLoS ONE
Total Knee Arthroplasty Outcomes
article

Association of intra-articular injection and knee arthroscopy prior to primary knee replacement with the timing and outcomes of surgery: Retrospective cohort study using data from the Clinical Practice Research Datalink GOLD database

Antonella Delmestri, John Broomfield, Andrew Judge, Setor K. Kunutsor, Ashley Blom, Michael Richard Whitehouse, Sion Glyn‐Jones, Matthew Strang
article en

Abstract

Steroid injection and knee arthroscopy prior to primary knee replacement are each associated with worse outcomes. The observed association of lower mortality risk is suggestive of confounding by indication. The observed associations in this study could be used to inform shared decision making with patients on the treatment pathway for knee osteoarthritis.

PLoS ONEVol. 19(11)
University of Leicester (GB), Leicester General Hospital (GB), University Hospitals Bristol NHS Foundation Trust (GB), Southmead Hospital (GB), Nuffield Orthopaedic Centre (GB), National Institute for Health and Care Research (GB), University of Bristol (GB), University of Oxford (GB), University of Sheffield (GB)
Good health and well-being
Openalex Percentile: Top 60%
Total Knee Arthroplasty Outcomes
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