Pharmacokinetics and Safety of Bictegravir in Pregnant and Postpartum Persons With HIV and Their Infants

Bictegravir exposure was lower during pregnancy compared with postpartum, yet C 24 concentrations were greater than the bictegravir protein-adjusted 95% effective concentration.

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Publication Details

Journal
JAIDS Journal of Acquired Immune Deficiency Syndromes
Published
2024-11-21
DOI
https://doi.org/10.1097/qai.0000000000003571
Citations
6
Primary Topic
HIV/AIDS drug development and treatment
Type
article
Field-Weighted Citation Impact
2.33
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article

Pharmacokinetics and Safety of Bictegravir in Pregnant and Postpartum Persons With HIV and Their Infants

Priyanka Arora, Lilia María Rizo Topete, Ahizechukwu Chigoziem Eke, David E. Shapiro et al.
6 citations
JAIDS Journal of Acquired Immune Deficiency Syndromes
HIV/AIDS drug development and treatment
2.33
article

Pharmacokinetics and Safety of Bictegravir in Pregnant and Postpartum Persons With HIV and Their Infants

Priyanka Arora, Lilia María Rizo Topete, Ahizechukwu Chigoziem Eke, David E. Shapiro, Jeremiah D. Momper, Kathleen M. Powis, Mauricio Pinilla, Kristina M. Brooks, Nahida Chakhtoura, Allison Agwu, Brookie M. Best, Xiao‐Ying Huang, Alice Marie Stek, Renee Browning, Kevin R. Knowles, Mark Mirochnick, Elizabeth Greene, Flynn McMorrow
article en
6 citations

Abstract

Bictegravir exposure was lower during pregnancy compared with postpartum, yet C 24 concentrations were greater than the bictegravir protein-adjusted 95% effective concentration.

JAIDS Journal of Acquired Immune Deficiency SyndromesVol. 98(3)
Boston University (US), University of Southern California (US), Family Health International 360 (US), Harvard University (US), Johns Hopkins University (US), Johns Hopkins Medicine (US), University of California San Diego (US), Rady Children's Hospital-San Diego (US), Massachusetts General Hospital (US), Cancer Research And Biostatistics (US), National Institute of Allergy and Infectious Diseases (US), Frontier Science & Technology Research Foundation, Inc. (US), Gilead Sciences (United States) (US), Eunice Kennedy Shriver National Institute of Child Health and Human Development (US), University of Colorado Anschutz Medical Campus (US), University of Montana (US)
Good health and well-being
Openalex Percentile: Top 11%
HIV/AIDS drug development and treatment
2.33
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