Microstructural Damage and Repair in the Spinal Cord of Patients With Early Multiple Sclerosis and Association With Disability at 5 Years
People with early relapsing-remitting MS exhibited heterogeneous profiles of microstructural SC damage and repair. Progression of microstructural damage was associated with disability progression and SC atrophy 5 years later. These results indicate a potential for microstructural repair in the SC to prevent disability progression in pwMS.
Authors
- Emmanuelle Le Page (ORCID: https://orcid.org/0000-0002-7849-2266)
- Bruno Stankoff (ORCID: https://orcid.org/0000-0002-9631-4674)
- Arthur Masson
- Élise Bannier (ORCID: https://orcid.org/0000-0002-8942-7486)
- Jean‐Christophe Ferré (ORCID: https://orcid.org/0000-0003-3911-1800)
- Anne Kerbrat (ORCID: https://orcid.org/0000-0002-4530-3553)
- Benedetta Bodini (ORCID: https://orcid.org/0000-0001-8010-1220)
- Benoît Combès (ORCID: https://orcid.org/0000-0003-4161-7093)
- Laure Michel (ORCID: https://orcid.org/0000-0002-8119-7794)
- Gilles Edan (ORCID: https://orcid.org/0000-0002-9641-6734)
- Vivien Caron
- Gaëlle Baudron
- Malo Gaubert
Institutions
- Centre National de la Recherche Scientifique (FR)
- Inserm (FR)
- Université Rennes 2 (FR)
- Sorbonne Université (FR)
- Assistance Publique – Hôpitaux de Paris (FR)
- Centre Hospitalier Universitaire de Rennes (FR)
Publication Details
- Journal
- Neurology Neuroimmunology & Neuroinflammation
- Published
- 2024-11-21
- DOI
- https://doi.org/10.1212/nxi.0000000000200333
- Citations
- 3
- Primary Topic
- Multiple Sclerosis Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 1.27
Funders
- Infrastructures en Biologie Santé et Agronomie
- Institut National de la Santé et de la Recherche Médicale
- Conseil Régional de Bretagne
- Centre National de la Recherche Scientifique
- Centre Hospitalier Universitaire de Rennes