The Impact of Sodium-Glucose Co-Transporter Type-2 Inhibitors on Alanine Aminotransferase Levels in Type-2 Diabetes Patients Having Features of Nonalcoholic Fatty Liver Disease: A Retrospective Cohort Study in Pakistan

We observed an average reduction in mean ALT levels when SGLT2Is was initiated in T2DM patients having NAFLD. Apart from encouraging diet and lifestyle modification, early intervention with SGLT2Is may decrease liver-related morbidity and mortality resulting from NAFLD.

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Publication Details

Journal
Pakistan Journal of Medical Sciences
Published
2024-11-21
DOI
https://doi.org/10.12669/pjms.40.11.8900
Primary Topic
Liver Disease Diagnosis and Treatment
Type
article
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article

The Impact of Sodium-Glucose Co-Transporter Type-2 Inhibitors on Alanine Aminotransferase Levels in Type-2 Diabetes Patients Having Features of Nonalcoholic Fatty Liver Disease: A Retrospective Cohort Study in Pakistan

Iqbal Azam, Uzma Khan, Asefa Shariq Ansari, Azra Rizwan
Pakistan Journal of Medical Sciences
Liver Disease Diagnosis and Treatment
article

The Impact of Sodium-Glucose Co-Transporter Type-2 Inhibitors on Alanine Aminotransferase Levels in Type-2 Diabetes Patients Having Features of Nonalcoholic Fatty Liver Disease: A Retrospective Cohort Study in Pakistan

Iqbal Azam, Uzma Khan, Asefa Shariq Ansari, Azra Rizwan
article en

Abstract

We observed an average reduction in mean ALT levels when SGLT2Is was initiated in T2DM patients having NAFLD. Apart from encouraging diet and lifestyle modification, early intervention with SGLT2Is may decrease liver-related morbidity and mortality resulting from NAFLD.

Pakistan Journal of Medical SciencesVol. 40(11)
Aga Khan University Hospital Nairobi (KE), Aga Khan University Hospital (PK), University of Mississippi Medical Center (US), Shaheed Zulfiqar Ali Bhutto Institute of Science and Technology (PK)
Good health and well-being
Openalex Percentile: Top 68%
Liver Disease Diagnosis and Treatment
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The Impact of Sodium-Glucose Co-Transporter Type-2 Inhibitors on Alanine Aminotransferase Levels in Type-2 Diabetes Patients Having Features of Nonalcoholic Fatty Liver Disease: A Retrospective Cohort Study in Pakistan — Iqbal Azam, Uzma Khan, et al. · Pakistan Journal of Medical Sciences (2024) | TGRS Research Map | TGRS