A case of adult ETV6-ASCL6 fusion gene positive chronic myeloproliferative tumor and literature review
ETV6-ASCL6 fusion gene plays an important role in hematopoiesis and hematological malignancies, but it is rare in hematological diseases. This paper describes a case of etv6-ascl6 fusion gene positive patient who was successively diagnosed as myelofibrosis, eosinophilic leukemia, basophilic leukemia and secondary acute myeloid leukemia. The clinical manifestations and disease evolution have its unique characteristics.
Authors
- Xian-hua Yuan (ORCID: https://orcid.org/0000-0002-0351-2285)
- Pei Wang (ORCID: https://orcid.org/0000-0002-3586-5130)
- W L Xu
- Yanmin Yang
Institutions
- Hebei Medical University (CN)
- Xingtai People's Hospital (CN)
- Xingtai Medical College
Publication Details
- Journal
- Pakistan Journal of Medical Sciences
- Published
- 2024-11-21
- DOI
- https://doi.org/10.12669/pjms.40.11.8556
- Primary Topic
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00