Pedunculoside alleviates cognitive deficits and neuronal cell apoptosis by activating the AMPK signaling cascade
The findings indicate that Ped exerts its neuroprotective effects against oxidative stress and apoptosis through the AMPK signaling cascade. The results demonstrate that Ped is a potential candidate for the treatment of AD.
Authors
- Lingyu She
- Jinfeng Sun (ORCID: https://orcid.org/0000-0002-5576-1654)
- Luyao Li (ORCID: https://orcid.org/0000-0002-0250-8428)
- Guang Liang (ORCID: https://orcid.org/0000-0002-8278-849X)
- Yuqing Zeng (ORCID: https://orcid.org/0000-0001-8768-4764)
- Xiong Li (ORCID: https://orcid.org/0000-0001-9614-7194)
- Wei Wang (ORCID: https://orcid.org/0000-0001-9829-7081)
- Liwei Li (ORCID: https://orcid.org/0009-0001-5978-874X)
- Hao Tang (ORCID: https://orcid.org/0000-0003-1709-5889)
- Fan Chen (ORCID: https://orcid.org/0009-0001-8972-793X)
- Xia Zhao (ORCID: https://orcid.org/0000-0002-2379-9447)
Institutions
- Yanbian University (CN)
- Wenzhou Medical University (CN)
- Zhejiang Provincial People's Hospital (CN)
- Hangzhou Medical College (CN)
Publication Details
- Journal
- Chinese Medicine
- Published
- 2024-11-22
- DOI
- https://doi.org/10.1186/s13020-024-01033-6
- Citations
- 8
- Primary Topic
- Alzheimer's disease research and treatments
- Type
- article
- Field-Weighted Citation Impact
- 2.61
Funders
- Zhejiang Key Laboratory of Pathophysiology
- Natural Science Foundation of Zhejiang Province