Pneumonitis after normofractionated radioimmunotherapy: a method for dosimetric evaluation
The proposed method was capable to quantify dosimetric differences in the dose-volume-effect relationship of PTP for patients with R(C)T + ICI and patients with R(C)T only. In this exploratory analysis, no significant dosimetric differences within PTP volumes for the different groups could be observed. However, our observations suggest, that for safe application of thoracic R(C)T + ICI, further careful investigation of dosimetric prescription and analysis concepts with larger and conformer study groups is recommendable.
Authors
- Kai Joachim Borm (ORCID: https://orcid.org/0009-0005-8580-890X)
- Kim Melanie Kraus (ORCID: https://orcid.org/0000-0003-3359-2316)
- Stephanie Elisabeth Combs (ORCID: https://orcid.org/0000-0002-6934-2864)
- Lisa Steinhelfer (ORCID: https://orcid.org/0000-0003-2452-4389)
- Benedikt Feuerecker
- Julius Fischer (ORCID: https://orcid.org/0000-0002-6951-3416)
- Denise Bernhardt (ORCID: https://orcid.org/0000-0001-5231-9097)
- Jan Caspar Peeken (ORCID: https://orcid.org/0000-0003-2679-9853)
- Caroline Bauer
- Juliana Martins
Institutions
- German Cancer Research Center (DE)
- TUM Klinikum (DE)
- Helmholtz Zentrum München (DE)
- LMU Klinikum (DE)
- München Klinik (DE)
- Technical University of Munich (DE)
- Ludwig-Maximilians-Universität München (DE)
Publication Details
- Journal
- Radiation Oncology
- Published
- 2024-11-21
- DOI
- https://doi.org/10.1186/s13014-024-02561-z
- Citations
- 1
- Primary Topic
- Radiopharmaceutical Chemistry and Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.40
Funders
- Technische Universität München
- Deutschen Konsortium für Translationale Krebsforschung