Morphofunctional Characteristics of Chinchilla lanigera Liver and Kidneys in the Setting of Hydrogen-Rich Water Regime

The article presents the results of including hydrogen-rich water in the diet of Chinchilla lanigera (longtailed chinchilla). The experiment was carried out on two groups of chinchillas: control (n=10) and experimental (n=10). The long-term scientific experiment covered the period of three years. At the beginning, in to determine the toxic effects of molecular hydrogen. To that end, laboratory investigations were conducted to assess the morphometry of the renal capillary glomeruli, characterizing the vascular bed, and to determine the area of hepatocytes, their nuclear-cytoplasmic ratio, as well as the stromal and parenchymal components of the liver. The long-term use of hydrogen-rich water was shown to contribute to a decrease in the area of the renal glomeruli of animals in the experimental group by 27% (p<0.01). In addition, an increase in the parenchymal component of the liver and the volume of cytoplasm in hepatocytes (p<0.01) was observed. It is concluded that the inclusion of hydrogen-rich water in the diet of animals has a beneficial effect on the condition of the renal glomeruli and vascular system and has no toxic effect on the liver.

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Journal
Journal Biomed
Published
2024-11-13
DOI
https://doi.org/10.33647/2713-0428-20-3e-70-76
Primary Topic
Hydrogen's biological and therapeutic effects
Type
article
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article

Morphofunctional Characteristics of Chinchilla lanigera Liver and Kidneys in the Setting of Hydrogen-Rich Water Regime

V. N. Karkischenko, D Petrov, Е. В. Панина, К.С. Остренко et al.
Journal Biomed
Hydrogen's biological and therapeutic effects
article

Morphofunctional Characteristics of Chinchilla lanigera Liver and Kidneys in the Setting of Hydrogen-Rich Water Regime

V. N. Karkischenko, D Petrov, Е. В. Панина, К.С. Остренко, A. E. Sorochan
article en

Abstract

The article presents the results of including hydrogen-rich water in the diet of Chinchilla lanigera (longtailed chinchilla). The experiment was carried out on two groups of chinchillas: control (n=10) and experimental (n=10). The long-term scientific experiment covered the period of three years. At the beginning, in to determine the toxic effects of molecular hydrogen. To that end, laboratory investigations were conducted to assess the morphometry of the renal capillary glomeruli, characterizing the vascular bed, and to determine the area of hepatocytes, their nuclear-cytoplasmic ratio, as well as the stromal and parenchymal components of the liver. The long-term use of hydrogen-rich water was shown to contribute to a decrease in the area of the renal glomeruli of animals in the experimental group by 27% (p<0.01). In addition, an increase in the parenchymal component of the liver and the volume of cytoplasm in hepatocytes (p<0.01) was observed. It is concluded that the inclusion of hydrogen-rich water in the diet of animals has a beneficial effect on the condition of the renal glomeruli and vascular system and has no toxic effect on the liver.

Journal BiomedVol. 20(3E)
Russian State Agrarian University - Moscow Timiryazev Agricultural Academy (RU), Moscow State Agroengineering University named after V.P. Goryachkin (RU), Federal Scientific Center for Animal Husbandry named after Academician L.K. Ernst (RU), Federal Medical-Biological Agency (RU)
Clean water and sanitation
Openalex Percentile: Top 60%
Hydrogen's biological and therapeutic effects
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