Pharmacokinetics of Methadone in Adult Patients Undergoing Cardiac Surgery With Cardiopulmonary Bypass
Our results confirmed a decay in methadone concentrations during CPB, which, in our modeling analysis, was attributed to hemodilution and sequestration within the CPB components.
Authors
- Rodrigo López (ORCID: https://orcid.org/0000-0003-3144-9954)
- María Francisca Elgueta (ORCID: https://orcid.org/0000-0001-5513-7408)
- Augusto Rolle
- Luis I. Cortínez (ORCID: https://orcid.org/0000-0001-8544-8768)
- Ady Giordano (ORCID: https://orcid.org/0000-0002-1867-6848)
- Víctor Contreras (ORCID: https://orcid.org/0000-0002-6081-0430)
- Wilbaldo Salas
- Brian J. Anderson
- Cesar Godoy
Institutions
- University of Auckland (NZ)
- Pontificia Universidad Católica de Chile (CL)
Publication Details
- Journal
- Anesthesia & Analgesia
- Published
- 2024-11-21
- DOI
- https://doi.org/10.1213/ane.0000000000007312
- Citations
- 3
- Primary Topic
- Pain Management and Opioid Use
- Type
- article
- Field-Weighted Citation Impact
- 1.92